Nasal Irrigation with Hypertonic Seawater Solutions of 2.3% NaCl: A Safe and Effective Treatment Modality for Optimal Symptom Management in ENT Diseases
Review article of clinical studies on 2.3% Hypertonic Seawater Solution as adjunct or monotherapy in different populations.
  • Outcomes in healthy population:
    • Increases mucociliary clearance and improves nasal function
  • Outcomes in ENT patients:
    • Efficacious in various types of rhinitis and sinusitis of acute, chronic, allergic or non-allergic aetiology
      • Increase in mucociliary clearance
      • Reduction of local edema
      • Superior efficacy to study control groups or isotonic solutions
    • Use in combination with prescribed medications allows optimal disease management & reduction of medication intaken
  • Outcomes in ESS patients:
    • Provides sinonasal symptomatic relief even in patients with aspirin-induced CRS
    • Improves nasal breathing and minimises risk of postoperative infections in septoplasty patients
    • Less nasal bleeding & crust formation in septoplasty patients with radiofrequency volume reductionn

Sinomarin is effective with a high level of safety, and can be used alone or in combination with prescribed medication for optimal disease management


Protopapadakis E., Georgiou S., Alevizopoulos K.. Nasal Irrigation with Hypertonic Seawater Solutions of 2.3% NaCl: A Safe and Effective Treatment Modality for Optimal Symptom Management in ENT Diseases. International Journal of Medical Studies and Clinical Case Reports, 26 April 2024

Study Details

Open, prospective observational, non-interventional study in adult patients with allergic rhinitis
 

Product tested: Sinomarin PA ENT & Hypertonic Adults

 
Total # of participants: 1.700
 
Güner Atayoğlu A et al., Investigation of the Effectiveness of Nasal Sprays in Allergic Rhinitis. Ear Nose Throat J. 2024 Nov;103(3_suppl):144S-151S. doi: 10.1177/01455613241287298. Epub 2024 Oct 10. PMID: 39390797.